Pre 4 Infect

Examples of antibiotics in the cephalosporin class include:

A. azithromycin, clarithromycin, erythromycin
B. amoxicillin, nafcillin, pipercillin
C. cefazolin, cephalexin, ceftriaxone
D. amikacin, gentamicin, tobramycin



Match the drug to its mechanism of action or target organism.

Rifampin a A inhibit nucleic acid synthesis
Trimethoprim c C interferes with folic acid metabolism
Cephalosporins b B inhibits cell wall synthesis



A patient who has been on antibiotics for several weeks now has an infection with fungus and a bacteria resistant to the antibiotic which was previously taken. This patient is said to have:

A. Viralemia.
B. A super-infection.
C. Multimicrobial Supplantation Syndrome
D. Prophylactic propagation



Patients who will be taking drugs to treat infection are instructed to take every dose as prescribed. The main reason for doing this is to:

A. Decrease the possibility of acquiring an allergy to the drug.
B. Manage the infection without developing resistance to the drug.
C. Prevent the patient from saving left over drug to use in a future infection when it may not be the appropriate choice.
D. Limit costs associated with drug therapy.



What teaching is important for patients receiving a tetracyline antibiotic?

A. Take with food or milk.
B. Narrow spectrum, superinfection unlikely.
C. Avoid exposure to sun.
D. Safe to use in pregnancy.

General Feedback: Tetracylines are broad spectrum so superinfection risk is relatively high. They bind divalent cations, such as iron or calcium so should not be taken with milk or absorption could be decreased by up to 50%! If used during pregnancy or under 9yo, it binds to calcium in bones and discolors teeth permananetly. it does make skin more sensitive to burning.



Examples of antibiotics in the penicillin class include:

A. cefazolin, cephalexin, ceftriaxone
B. azithromycin, clarithromycin, erythromycin
C. amoxicillin, nafcillin, pipercillin
D. amikacin, gentamicin, tobramycin



Resistance to antibiotics can be minimized by:
A. early treatment of all viral infections.
B. limiting use of prophylactic antibiotics.
C. teaching patients to stop taking the antibiotic when the symptoms of infection resolve.
D. using broad spectrum antibiotics whenever possible




Match the drug to its main mechanism of action.

Penicillin a. inhibit nucleic acid syntheisis

Sulfonamides b. inhibit cell wall synthesis

Aminoglycosides c. antimetabolite, competition for folate

Flouroquinolones d. inhibit protein synthesis



A "superinfection" refers to:

A. An infection with a resistant organism.
B. The presence of several different organisms in an infected site.
C. Overgrowth of undesired microbes when normal flora has been destroyed by antibiotic therapy.
D. Infection with a fungus.